The United States has imposed sanctions on two fugitive sons of Joaquin “El Chapo” Guzman and offered rewards of up to $10 million each for information leading to their arrest or conviction. The Treasury Department says Iván Archivaldo Guzman Salazar and Jesus Alfredo Guzman Salazar are believed to be in Mexico and are part of the wider “Chapitos” network that US authorities blame for helping drive fentanyl trafficking into the United States.
The sanctions also target the Chapitos faction itself, plus a regional group of associates and businesses based in Mazatlan that the Treasury says are involved in drug trafficking, extortion and money laundering. That gives the move more than symbolic weight. It is not just an action against two individuals, but an attempt to disrupt the financial and operational ecosystem around one of Mexico’s most powerful criminal organizations.
Treasury Secretary Scott Bessent framed the move as part of President Trump’s mandate to eliminate cartels and confront violent leaders tied to the Sinaloa Cartel. The cartel, one of Mexico’s oldest criminal groups, has turned fentanyl production into one of its most lucrative businesses and is blamed for tens of thousands of overdose deaths each year in the United States. In that sense, the sanctions sit inside a broader American effort to treat drug cartels not just as law-enforcement problems but as strategic threats.
The situation inside the family is more complicated. Two other sons, Joaquin Guzman Lopez and Ovidio Guzman Lopez, are already incarcerated in the United States. The AP report notes that prosecutors have said they will not seek the death penalty for Joaquin Guzman Lopez if he is convicted in Chicago. That detail underscores how many strands of the cartel case now run through US courts, prisons and asset-freeze measures.
The rewards program is also part of the strategy. Mexican security analyst David Saucedo told AP that payouts and witness protection have become an important tool for breaking apart criminal organizations because insiders can be tempted to cooperate once the money is on the table. The underlying idea is straightforward: pressure the financial base, reward informants and make it harder for cartel leaders to move with impunity.
Mexico’s foreign ministry did not immediately comment, and the AP report does not suggest any immediate operational effect from the sanctions. But the policy sends a clear message. Washington is aiming not only at cartel leadership in the abstract, but at the broader business network that allows the Sinaloa Cartel to keep making money while its top figures remain out of reach.
The sanctions fit a wider US strategy of pressure and disruption rather than a single arrest attempt. By targeting both people and associated businesses, Washington is trying to make life harder for the network around the Guzman family, not just the fugitives themselves. Whether that works will depend on informants, enforcement and the ability of US and Mexican authorities to keep chipping away at the cartel’s finances.
The reward offers are meant to make that pressure immediate, not abstract.



